Resumen
Combination comprising polymyxin B and sphingosine. The present invention relates to a combination comprising polymyxin B (PMB) and sphingosine (Sph) for the treatment of bacterial infections, and especially respiratory infections caused by Gram-negative microorganisms. The synergistic effect of this combination allows for the use of lower quantities of both compounds than would be used if each compound were administered alone, as well as for the treatment of infections caused by bacteria that are multi-resistant to antimicrobials. The invention also relates to a pharmaceutical composition comprising a combination of PMB and Sph for administration by inhalation and/or intranasal route. (Machine-translation by Google Translate, not legally binding)