Resumen
Determination of methylation and levels of a mirna in response to an antitumor compound based on platinum. The present invention relates to a method for determining the response to a platinum-based antitumor compound in an ovarian cancer patient comprising (I) determining the level of methylation on the cpg island of sequence seq id no: 1 and (II) ) compare the level of methylation on said cpg island in the gene encoding mir-7 or the expression level of mir-7 with a corresponding reference value, where an increase in the level of methylation obtained in (I) or a decrease in the level of expression obtained in (I) with respect to the corresponding reference value, is indicative that the ovarian cancer of said patient is resistant to said platinum compound. The invention also relates to the use of mir-7 or a precursor thereof for the manufacture of a medicament for the treatment of a subject suffering from a cancer resistant to an anti-tumor compound based on platinum. (Machine-translation by Google Translate, not legally binding)