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Derivatives of p- hydroxy phenyl propionic acid as antiproliferative agentsCM Patents

Índice de la ficha

Updated at
24/07/2026
Numero publicacion
EP.1284263.A1
Fecha publicacion
19/02/2003
Numero solicitud
EP20010911771

En detalle

Resumen

The invention relates to derivatives of p- hydroxy phenyl propionic acid, which are characterized in that they contain general formulae (I) and (Ia), wherein the value of n may be 1,2 or 3; R may be H or CH3 and R1 may be CH3 or H with pharmacological activity. The invention also relates to the use of said derivatives in the treatment of disorders of the immunological system.

Reivindicaciones

1. Derivatives of the compound, <img class="EMIRef" id="449574451-ib0034" /> characterised in that they have the following general formula: <img class="EMIRef" id="449574451-ib0035" /> where n can take the values 1,2,3; R can be H or CH<3> and R1 can be CH<3> or H. 2. Compounds according to claim 1 presenting any of the possible combinations among the different values of n and the structures corresponding to the radicals R and R1. 3. Derivatives of the compound, <img class="EMIRef" id="449574451-ib0036" /> characterised in that they have the following general formula: <img class="EMIRef" id="449574451-ib0037" /> where n can take the values 1,2,3; R can be H or CH<3> and R1 can be CH<3> or H. 4. Compounds according to claim 3 presenting any of the possible combinations among the different values of n and the structures corresponding to the radicals R and R1. 5. Compounds according to claims 1 and 3 with pharmacological activity and their application in medicine for the treatment of disorders of the immunological system. 6. Compounds according to claims 1 and 3 and their application in pharmacy for their use in the preparation of the usual galenic forms including in them the original compounds and pro-drugs such as esters, glycosides, etc.

Etiquetas

Inventores
Barrera Jaime BermejoSilva Margarita HernandezMon Melchor Alvarez deRanieri Juan Pablo PivelJaime Bermejo BarreraMargarita Hernandez SilvaMelchor Alvarez de MonJuan Pablo Pivel RanieriBermejo Barrera JHernandez Silva MAlvarez de Mon MelchorPivel Ranieri Juan PabloBermejo Barrera JaimeHernandez Silva MargaritaPivel Ranierir Juan PabloPivel Ranieri JuanPivel Ranieri, Juan PabloDe Mon Melchor Alvarez
Solicitantes
Consejo Superior de Investigaciones CientíficasInvestig y Medicina SlSaetabis Bio ConsultingSaetabis Bio Consulting XativaConsejo Superior de Investigaciones Cientificas, MadridConsejo Superior de Inv3StigacConsejo Superior de Inv3Stigaciones CientificasBarrera Jaime BermejoSilva Margarita HernandezDe Mon Melchor AlvarezRanieri Juan Pablo PivelBermejo Barrera JaimeHernandez Silva MargaritaAlvarez de Mon MelchorPivel Ranieri Juan Pablo
Clasificacion ipc
A61K 31/ 365 A IA61P 37/ 00 A IC07D 307/ 58 A I
Clasificacion cpc
514/473549/323
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