Resumen
Use of compounds that bind tau microtubule binding domain in the manufacture of pharmaceutical compositions, said pharmaceutical compositions and their application in the treatment of tauopathies. The present invention is based on the fact that heparin inhibits the neuronal toxicity of the tau protein. Thus, the invention describes the use of a compound that binds to the microtubule binding domain of the tau protein, preferably heparin, in the manufacture of medicaments; and a pharmaceutical composition for the prophylaxis and/or treatment of tauopathies, preferably for the treatment of alzheimer's disease in humans. (Machine-translation by Google Translate, not legally binding)