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Derivatives of p- hydroxy phenyl propionic acid as antiproliferative agentsCM Patents

The invention relates to derivatives of p- hydroxy phenyl propionic acid, which are characterized in that they contain general formulae (I) and (Ia), wherein the value of n may be 1,2 or 3; R may be H or CH3 and R1 may be CH3 or H with pharmacological activity. The invention also relates to the use of said derivatives in the treatment of disorders of the immunological system.

Datos clave

CategoríaInvención

Índice de la ficha

Updated at
05/11/2026
Numero publicacion
EP.1284263.A1
Fecha publicacion
19/02/2003
Anio publicacion
2003

En detalle

Reivindicaciones

1. Derivatives of the compound, <img class="EMIRef" id="449574451-ib0034" /> characterised in that they have the following general formula: <img class="EMIRef" id="449574451-ib0035" /> where n can take the values 1,2,3; R can be H or CH<3> and R1 can be CH<3> or H. 2. Compounds according to claim 1 presenting any of the possible combinations among the different values of n and the structures corresponding to the radicals R and R1. 3. Derivatives of the compound, <img class="EMIRef" id="449574451-ib0036" /> characterised in that they have the following general formula: <img class="EMIRef" id="449574451-ib0037" /> where n can take the values 1,2,3; R can be H or CH<3> and R1 can be CH<3> or H. 4. Compounds according to claim 3 presenting any of the possible combinations among the different values of n and the structures corresponding to the radicals R and R1. 5. Compounds according to claims 1 and 3 with pharmacological activity and their application in medicine for the treatment of disorders of the immunological system. 6. Compounds according to claims 1 and 3 and their application in pharmacy for their use in the preparation of the usual galenic forms including in them the original compounds and pro-drugs such as esters, glycosides, etc.

Etiquetas

Inventores
Jaime Bermejo BarreraBarrera Jaime BermejoSilva Margarita HernandezMargarita Hernandez SilvaMon Melchor Alvarez deMelchor Alvarez de MonRanieri Juan Pablo PivelJuan Pablo Pivel RanieriBermejo Barrera JBermejo Barrera, J.Hernandez Silva MHernandez Silva, MAlvarez de Mon, MelchorAlvarez de Mon MelchorPivel Ranieri Juan PabloPivel Ranieri, Juan PabloBermejo Barrera JaimeHernandez Silva MargaritaPivel Ranierir Juan PabloPivel Ranieri JuanDe Mon Melchor AlvarezBermejo Barrera, JaimeHernandez Silva, MargaritaPivel Ranieri, Juan, Pablo
Solicitantes
Consejo Superior de Investigaciones CientíficasInvestig y Medicina S.L.Saetabis Bio ConsultingSaetabis Bio Consulting, XativaConsejo Superior de Inv3Stigac
Clasificacion ipc
A61K 31/ 365 A IA61P 37/ 00 A IC07D 307/ 58 A I
Clasificacion cpc
514/473549/323
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