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USE OF IGF-1 AS A REAGENT FOR EARLY DIAGNOSIS AND/OR PROGNOSIS OF ALZHEIMER DISEASECM Patents

[0001] The invention relates to the use of the insulin-like growth factor (IGF-1) as a reagent for the early diagnosis and/or prognosis of Alzheimer disease, to a kit comprising IGF-1 and a sedative, and to the use thereof in the early diagnosis and/or prognosis of Alzheimer disease.

Datos clave

CategoríaInvención

Índice de la ficha

Updated at
05/11/2026
Numero publicacion
EP.2957910.A1
Fecha publicacion
23/12/2015
Anio publicacion
2015
Numero solicitud
EP20140751079

En detalle

Reivindicaciones

1. Use of insulin-like growth factor-1 (IGF-1) as early diagnostic and/or prognostic reagent of Alzheimer's disease. 2. Use according to claim 1, wherein the concentration of IGF-1 is between 50 and 300 µg/kg, in particular, between 100 and 250 µg/kg. 3. Use according to claim 2, wherein the concentration of IGF-1 is 150 µg/kg. 4. Use according to any of claims 1 to 3, wherein IGF-1 is sequentially used with a sedative. 5. Use according to claim 4, wherein the sedative belongs to the group of benzodiazepines. 6. Use according to claim 5, where the sedative is selected from the group consisting of triazolam, oxazolam, estazolam, diazepam, lorazepam, lormetazepam, bentazepam, flurazepam, flunitrazepam, clonazepam clorazepate dipotassium and chlordiazepoxide. 7. Kit comprising insulin-like growth factor-1 (IGF-1) and a sedative. 8. Kit according to claim 7, wherein the concentration of IGF-1 is between 50 and 300 µg/kg, in particular, between 100 and 250 µg/kg. 9. Kit according to claim 8, wherein the concentration of IGF-1 is 150 µg/kg. 10. Kit according to any of claims 7 to 9, wherein the sedative belongs to the group of benzodiazepines. 11. Kit according to claim 10, wherein the sedative is selected from the group consisting of triazolam, oxazolam, estazolam, diazepam, lorazepam, lormetazepam, bentazepam, flurazepam, flunitrazepam, clonazepam clorazepate dipotassium and chlordiazepoxide. 12. Kit according to any of claims 7 to 11, comprising compounds for the determination of the blood glucose. 13. Kit according to claim 12, where the compounds for the determination of the blood glucose are reactive strips. 14. Use of a kit according to any of claims 7 to 13, for the early diagnosis and/or prognosis of Alzheimer's disease.

Etiquetas

Inventores
Trueba Saiz AngelTrueba Saiz, AngelTorres Aleman IgnacioTorres Aleman, IgnacioCavada Martinez, CarmenCavada Martinez CarmenNuñez Molina AngelNuñez Molina, Angel
Solicitantes
Consejo Superior de Investigaciones CientíficasUniversidad Autónoma de Madrid
Clasificacion ipc
A61K 31/ 5513 A IA61K 38/ 30 A IG01N 33/ 53 A IG01N 33/ 68 A I
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